Numerous analytical and numerical studies have analyzed the metering section of single-screw extruders. Due to substantial mathematical difficulities, all these analyses were based on specific model simplifications (e.g., Newtonian flow, isothermal flow, infinite channel width). We present a comprehensive numerical parameter study analyzing the three-dimensional, fully developed flow of polymer melts in metering sections. The pseudo-plastic nature is approximated by a power law model. Varying the influence parameters h/w (height-to-width ratio), t/D (pitch-to-diameter ratio), n (power law index), and Pp,z (dimensionless pressure gradient), a total number of 44 640 set-ups derived from similitude theory were simulated. For each design point, both the throughput and dissipation rate were evaluated. The calculated data set provides a powerful tool to predicting the conveying behavior of melt-conveying zones of single-screw extruders.