The main objective of this communication is to address a state of the art on recent advances in biopolymer multiphase systems based on PLA. Through this work, we present some promising routes to enhance its processing ability, which presents several challenges mainly due to the poor shear and elongation properties of this biopolymer. To our knowledge, there is no paper dedicated to the investigation of foaming and/or blown extrusion of PLA that involves structural, rheological and thermo-mechanical properties. Two main routes were selected: (i) the modification of its structure, rheological and thermo-mechanical properties and (ii) blending it with other ductile thermoplastic biopolymer such as the poly (butylene adipate-co-terephtalate) (PBAT) or polyamide (PA11). Various formulations of PLA with multifunctionalized epoxy, nucleants and plasticizer were prepared and characterized on the basis of their linear viscoelasticity and extensional properties. The balance of chain extension and branching has also been investigated using solution viscosimetry, steric exclusion chromatography (SEC) and rheology (Shear and elongation rheology). On one hand, a batch foaming assisted with supercritical CO2 was achieved. The influence of the foaming parameters, the extent of chain modification as well as the contribution of crystallization on cell morphology was evaluated. Based on these parameters, structures ranging from micro to macro-cellular-cell were obtained. On the other hand, the stability maps of blown processing for neat and modified PLA were established at different die temperatures. We have achieved a great enhancement of the blown processing windows of PLA with high BUR (Blow Up Ratio) and TUR (Take Up Ratio) attained. We were able to demonstrate that a higher kinetic of crystallization can also be reached for chain-extended and branched PLA formulated with adequate amounts of nucleants and plasticizers. Through this work, blown films with interesting thermo-mechanical and mechanical properties have been produced using an optimal formulation for PLA