Advances in controlled polymer synthesis, which provides a unique set of properties required for a targeted application, have expanded the scope of synthetic polymer applications. A class of synthetic polymers with unique and predictable properties obtained via controlled polymer synthesis are polyoxazolines. Polyoxazolines are synthesized from oxazoline monomers via cationic ring opening polymerization (CROP). The versatility of oxazoline monomers, initiators, and terminating agents used in the synthesis of polyoxazolines and the precise control of the molecular weight, polydispersity, composition, functionality, and topology of polyoxazolines make it possible to use these polymers in a wide range of applications. Tailor-made polyoxazolines have recently been used for tissue engineering, drug delivery, regenerative medicine, wound healing, and gene therapy applications in biomedical industry. This presentation will mainly discuss the development of a versatile technology platform based on oxazoline chemistry and its utilization as advanced drug delivery systems for the treatment of Parkinson’s Disease and cancer. The utilization of the platform as thermally latent catalyst systems for composites in a completely new application area will also be briefly discussed in order to demonstrate the versatility and the broad application potential of this platform.