A low friction coefficient causes the use of polytetrafluoroethylene (PTFE) as solid lubricant in antifriction coatings as well as in tribological bulk materials. However, it is well known that PTFE is not compatible to almost all plastic materials. For that reason a homogeneous distribution and breaking down of PTFE particles in a polyetherimide (PEI) matrix to generate anti-friction coatings is not successful without adding of any dispersion stabilizer. The objective of our research was to use Gamma- irradiated and, for comparison, non-modified PTFE- powder to generate PEI-PTFE antifriction coatings and to compare several approaches to get an improved breaking down behavior and homogeneous distribution of the PTFE particles. Two different approaches were studied to get homogeneous distributed PTFE particles in the matrix material: - Reactive extrusion of Gamma-modified PTFE with PEI followed by a high power dispersion procedure - High power dispersion of Gamma- modified/ non modified PTFE It was already found in the past that a defined high energy irradiation of PTFE powder results in a generation of reactive functional groups or persistent radicals. These species are able to form chemical bonding to the polyetherimide matrix. The high shear rate in the extrusion procedure enables a higher bonding degree in comparison to a high power mixing of both components during dispersion. The bonding was proved by FTIR-spectroscopy and SEM micrographs. The thus obtained PEI-PTFE-cg pellets were subsequently used for the formulation of solvent-based dispersions. The dispersions were characterized for their rheological properties, dispersion stability and particle size distribution. It was demonstrated that chemical bonding between PTFE and PEI results in very stable dispersions without adding of any dispersion agent. Furthermore, the resulting particle size is much lower and the particle size distribution is more homogeneous than in physical mixtures of PTFE powder.