The processing technique of layer multiplication co-extrusion has proven its worth many fold in the area of advanced barrier properties. However, historically, only extrudates in sheet or film form were able to be produced. In this work we further develop our recent pioneer extension to multi-layered tubes and pipes with high barrier properties. With the utilization of multi-layer film production of barrier materials and a custom fuel permeation testing technique, optimal barrier films are defined. Optimal systems are then extruded in the form of tubing utilizing a custom tubing die designed for the layer multiplication system. Systems of 257 – 1025 layers in annular form show good layer uniformity and structure. A cap laying die is then designed for the purpose for reducing the layer structure thickness within the tubing to an optimal layer thickness based on film testing. This technique is then implemented in one of the optimal material systems in tube form. Initial observations indicate that successful layering and much enhanced barrier properties may be achieved by this method. This work also points to some of the revolutionary possible developments in other areas, such as multi-layered extrusion blow-molding.