Micro-injection molding is frequently used in micro-medical, micro-optic and micro-mechanics due to its effectiveness for mass production. This work focuses mainly on offering numerical tools to model the injection of textured molds. Such tools can predict the different filling scenarios of the micro-details and consequently offer optimal operating conditions (mold and melt temperatures, melt flow, stresses etc.) to judge the final part quality. To do so, a fully Eulerian approach is used to model the injection of textured molds on both the macroscopic and microscopic scales as usual industrial software cannot handle the filling the micro details. Since the thermal transfers with the mold are very relevant due to the cooling ratio, the coupling between micro- and macro- simulations are a must to insure a complete and accurate representation of textured molds injection. The influence most important parameters are studied and comparisons with experiment data are presented.