The Nanomanufacturing Center at UMass Lowell has developed processes to enable the nanomanufacturing of polymer based products. Bulk properties can be tailored for preparing novel nanomaterials for use printing materials or as substrates. This work will focus on the ability to tailor the surface for specific applications or enabling the printing of structures onto the substrate. For example, the surface chemistry and structure can be tailored for superhydrophobic or omniphobic properties. Tailored surfaces for controlling the printing of secondary structures by patterning of hydrophobic and hydrophilic surface patterns as well as nano or micro-structured surfaces with patterns of different polymers or nanoparticles can be made with directed assembly and transfer to a polymer substrate. The process can be scaled to a roll to roll process. A critical aspect is the transfer process, which is controlled by the interfacial attraction between the substrate and the patterned nanomaterial and the process parameters (melt temperature, rates). These structures can be used in applications such as metamaterials, flexible electronics, sensors, and structural materials. The environmental, health, and safety aspects of nanomanufacturing are also addressed.