In-depth understanding of structural change and morphological development in polymer subjected to thermo-mechanical fields is always the main emphasis in the research of polymer engineering and high performance modification. Our work mainly focus on large scale formation and control of hybrid shish-kebab structures in polyethylene/Carbon Nano-fiber (HDPE/CNF) blends subjected to secondary melt flow. A strong shear flow was imposed on the melt of CNF reinforced HDPE during a secondary melt flow process, i.e. gas assisted injection molding (GAIM). Large scale hybrid shish-kebabs (HSK) were directly formed in the entire thickness of the GAIM HDPE/CNF composites, which were closely related to the strong shear flow that was further amplified and distributed by incorporated CNF. Interestingly, the long axis of CNFs is parallel to the shear flow direction, the lamellae of HDPE is perpendicular to long axis of CNFs. The three-step mechanism, including (1) the orientation of both HDPE and CNF, (2) first formation of HDPE extend-chain shish directly nucleated on CNFs surface then followed by nucleation of folded-chian lamellae, and (3) the crystallization of HDPE kebabs on the HDPE decorated CNFs. Importantly, the HSK structure can bring significant mechanical reinforcement in the HDPE/CNFs composite. Keywords: Polyethylene; carbon nano-fiber; Hybrid shish-kebab