Today, the majority of industrially employed isotactic polypropylene (iPP) are produced using MgCl2 supported Ziegler Natta (ZN) catalysts in combination with bulk and/or gas phase polymerization technologies, among them the Borstar® process by Borealis. Some polyolefin application areas require that resins have a good processability in combination with a very high purity and crystallinity. Good processability is of particular importance in the very demanding conversion process used for the preparation of biaxially oriented PP (BOPP) films. The property profile of the resin is strongly dependent on both the catalyst and the technology used to produce it. A bench scale study was conducted using design of experiments methodology to evaluate the capability of three current generation ZN catalysts under Borstar® conditions to produce iPPs suitable to the above criteria. The polymerization conditions were systematically varied to generate a set of polypropylenes obtained per catalyst which differed in their property profiles. Several key polymer properties (such as purity, chain microstructure, crystallinity and melting behavior) were investigated and correlated to the polymerization conditions. As a small scale application test, biaxial orientation experiments were performed using a laboratory scale biaxial orientation device on compression molded plates. The effect of catalyst and polymer structure on the biaxial stress strain behavior was clearly observable. Results of this study illustrate how application properties of polyolefins can be tuned by using different catalysts and varying polymerization conditions.