Due to environmental concerns, the zinc content in rubber compounds is under research, since it may cause adverse effects in the aquatic systems. The fossil processing oils are also being replaced because tire treads materials are spread on roadsides, releasing great amounts of polycyclic aromatic hydrocarbons in the environment. In this study, the use of substituting materials to zinc oxide and plasticizer was evaluated, aiming at reducing the amount of these compounds in a standard natural rubber formulation to retreading treads. Zinc oxide was replaced by organic zinc in the proportions of 2 to 5 phr, and the plasticizer was replaced by vegetable oil in the proportions of 3 to 8 phr. It was also evaluated a formulation with vegetable oil (4 phr) along with organic zinc (3 phr). The vulcanization parameters were obtained by oscillatory disc rheometry. Mechanical properties were evaluated by tensile and tear strength, hardness and abrasion loss. The obtained results were compared to a standard formulation of zinc oxide and naphthenic oil. The compounds with vegetable oil and organic zinc presented minimum and maximum torque values close to the standard sample, indicating a small variation in the viscosity and crosslink density. The scorch and vulcanization time were similar for all the samples with vegetable oil. The samples with 2 phr of organic zinc presented higher cure rate values, indicating lower time of vulcanization and an economy of the process. The mechanical properties indicated an increase in elongation at break and tensile strength, lower abrasion wear and hardness with 4 phr of vegetable oil. Tear strength values were similar, making also possible reducing the amount of plasticizer in the formulation. The results showed that was possible to reduce the oil and zinc content in the formulations, obtaining better mechanical properties comparing to the standard formulation containing naphthenic oil and zinc oxide.