The research and development (R&D) in rubber formulation development requires reproducible, repeatable, fast, accurate and efficient sample preparation. The lab-scale formulation development is conventionally carried out using small scale internal mixers and two-roll mills. However, high torque laboratory twin-screw micro-compounder, which have been serving for plastic industry more than 30 years, can be used to formulate new rubber compounds for fast and accurate sample preparation that on top can contribute to the economics of R&D. In this study we investigated the possibility of using lab-scale 15 mL twin-screw micro-compounder as a tool for new rubber compound development. For this purpose we formulated an EPDM/Carbon black recipe through conventional way using a Banbury mixer followed by two-roll mill, and through the potential way using a lab-scale 15 mL twin-screw micro-compounder. We crosslinked both systems via hot press at a predefined temperature and time. The rheological and mechanical properties of the compounds were investigated. Moreover the dispersion of carbon black in EPDM matrix was judged by dispergrader and electron microscope. The conventional way of sample preparation was compared with a potential way of sample preparation based on materials parameters and ease of operation as well.