Polymer electrolyte membrane fuel cell has been considered as an alternative type of fuel cell compared to its liquid electrolyte counterpart. This is due to the membrane multifunctional ability of the membrane electrolyte. The triple role of the membrane include (i) charge carrier for ions, (ii) avoid fuel crossover/permeability, and (iii) electronic insulator to prevent parasitic losses due to passage of electrons through the membrane. Unfortunately the Polymer electrolyte membranes still suffers from fuel crossover/permeability, low ion conductivity and dehydration during operation. To address these challenges, nanostructured materials such as, carbon nanotubes, TiO2, ZnO, nanofibers, graphene oxide have been integrated in the polymer matrix to form a nano-enabled composite membranes. The membranes fabricated in this study were found to have improved basic properties for fuel cell application; methanol crossover reduced, ion conductivity increased and water hydration improved, which lead to an enhanced peak power density. This study offers a promising route to greatly enhance the polymer electrolyte membrane properties and provides insights on the influence of nanostructured materials on the electrolyte membrane for fuel cell application.