Despite the profound features of polylactide (PLA) such as being originated from renewable resources and its biodegradability, PLA has several drawbacks that limit its usage for different commodity and engineering applications. A series of these drawbacks could be according to the PLA’s glass transition temperature (Tg ~ 60oC) and its very slow crystallization. In applications where the service temperature requires to be below 60oC, PLA behaves as a very brittle polymer whereas in those cases where the service temperature should be beyond 60oC, PLA can easily be deflected by heat because the degree of crystallinity is not high enough to provide the required rigidity. Moreover, a series of drawbacks originate from the PLA’s melt conditions. Due to its very low melt strength followed by its slow crystallization rate, PLA possesses very poor ability to be processed and formed. Similar scenario exists in processing of PLA/gas mixtures to form high-quality foamed structures. In this work, recent enhancements in recovering the PLA’s drawbacks are discussed. It has been shown how the foaming behavior of PLA can be improved through various approaches, how blending PLA with other biodegradable polymers and nanofillers could influence the PLA’s final properties, and eventually, a new approach on how self-reinforcing could be introduced in PLA-based systems to overcome its viscoelastic properties and hence its processability. The last approach, which is based on development of a new PLA resin through blending certain PLA grades, provides a new route to extend the PLA’s usage in much wider applications without requiring extra expensive additives.