pps proceeding - Abstract Preview
pps proceeding
Symposium: S03 - Polymer-based Nanostructured Materials
Poster Presentation
 
 

Viscoelastic behavior of Calcium Phosphate Packed Bacterial Cellulose -Polyvinylpyrrolidone based Hydrogel Scaffolds at Human Fever Temperature

Basu Probal (1), Saha Nabanita (2)*, Zaandra Oyunchimeg (1), Saha Petr (1)

(1) Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, - Zlin - Czech, (2) Centre of Polymer Systems,University Institute, Tomas Bata University in Zlin, - Zlin - Czech

Calcium phosphate (CaP) filled bacterial cellulose (BC) and polyvinylpyrrolidone (PVP) based hydrogel scaffolds (BC-PVP-CaP) are being reported here considering its possible application in bone restoration. The primary focus of this work is to analyze the viscoelastic behavior of ‘BC-PVP-CaP’ hydrogel scaffolds at human fever temperature condition (39 degree C) in swelled state. In BC-PVP scaffolds, CaP is present in the form of β-tricalcium phosphate (β-TCP) and hydroxyapatite (HA) in different concentrations (i.e. β-TCP/HA_20:80, β-TCP/HA_40:60, β-TCP/HA_50:50). During evaluation of viscoelasticity, BC-PVP scaffold (without CaP) was marked as a control set. The BC-PVP-CaP_50:50 hydrogel scaffold showed the highest degree of swelling at 39 degree C among the other BC-PVP-CaP scaffolds. Regardless of it, the other hydrogel scaffolds were also showed notable viscoelasticity at 39 degree C. Experimental results confirmed that all the CaP filled BC-PVP hydrogel scaffolds (BC-PVP-CaP_20:80, BC-PVP-CaP_40:60, BC-PVP-CaP_50:50) exhibit a promising swelling and viscoelastic behavior at human fever temperature condition (39 degree C), can be endorsed for its potential application in bone repairing /bone restoration. Keywords: Bacterial cellulose, calcium phosphate, viscoelasticity, human fever temperature, bone restoration ACKNOWLEDGEMENTS This work is supported by the Internal Grant Agency (Project No. IGA/CPS/2019/003), Tomas Bata University in Zlin, Czech Republic and Ministry of Education, Youth and Sports of the Czech Republic – NPU Program I (LO1504).