Due to a growing environmental awareness, industries have started to seek more ecologically friendly materials to replace conventional materials. Natural fibers have caught attention as reinforcement for natural fiber composites due to many advantages compared to synthetic fibers. For example, low weight, biodegradability, availability and good mechanical properties. However, natural fibers also show important disadvantages, being their low compatibility with hydrophobic polymer matrices the most important one. To improve the poor interaction between natural fibers and polymeric matrices, fibers can be chemically treated. Among chemical treatments, the use of alkaline solutions (mercerization), and maleated polyolefins (coupling agents) are the most commonly used. Mercerization gives place to a rougher and more porous fiber surface, enhancing the mechanical interlocking adhesion of the fibers with the matrix. However, this treatment could lead to a decrease in the natural mechanical properties of fiber. Mercerization is also considered a pre-stage to improve the effect of any further chemical treatment. Mercerized fibers are commonly treated with coupling agents (e.g. maleic anhydride grafted polyethylene, MAPE) added to modify not only the fiber surface but also the thermoplastic matrix. The presence of metallic nanoparticles on the surface of chemically treated natural fibers could confer a wide range of macroscopic properties to the fibers such as antibacterial activity, conductivity and improved mechanical resistance, contributing to make natural fibers hydrophobic, improving their compatibility with polymer matrices. Thus, in this work, silver nanoparticles (AgNPs) were synthesized using untreated, mercerized and MAPE-treated Agave tequilana Weber var. Azul (AT) fibers. Results indicate that AgNPs can be succesfully synthesized using untreated and treated AT fibers, and that the tensile mechanical propeties of such fibers improve with the presence of AgNPs.